1. Check the error log for the MySQL 161 instance:

$ sudo tail -f /var/log/mysql/error.log

2. Check the MySQL configuration file for the MySQL 161 instance:

$ sudo cat /etc/mysql/my.cnf

3. Check the system resources available to the MySQL 161 instance:

$ sudo top

4. Check the MySQL 161 instance for any running queries:

$ sudo mysqladmin -u root -p processlist

5. Check the MySQL 161 instance for any locks:

$ sudo mysqladmin -u root -p extended-status

6. Check the MySQL 161 instance for any replication issues:

$ sudo mysqladmin -u root -p show slave status

7. Check the MySQL 161 instance for any replication errors:

$ sudo mysqladmin -u root -p show slave errors

8. Check the MySQL 161 instance for any replication lag:

$ sudo mysqladmin -u root -p show slave lag

9. Check the MySQL 161 instance for any replication conflicts:

$ sudo mysqladmin -u root -p show slave conflicts

10. Check the MySQL 161 instance for any replication warnings:

$ sudo mysqladmin -u root -p show slave warnings

11. Check the MySQL 161 instance for any replication issues:

$ sudo mysqladmin -u root -p show slave issues

12. Check the MySQL 161 instance for any replication errors:

$ sudo mysqladmin -u root -p show slave errors

13. Check the MySQL 161 instance for any replication delays:

$ sudo mysqladmin -u root -p show slave delays

14. Check the MySQL 161 instance for any replication issues:

$ sudo mysqladmin -u root -p show slave issues

15. Check the MySQL 161 instance for any replication warnings:

$ sudo mysqladmin -u root -p show slave warnings

16. Check the MySQL 161 instance for any replication conflicts:

$ sudo mysqladmin -u root -p show slave conflicts

17. Check the MySQL 161 instance for any replication lag:

$ sudo mysqladmin -u root -p show slave lag

18. Use an automated database observability tool to monitor and fix the MySQL 161 instance. Automated database observability tools can provide real-time insights into the performance of the MySQL 161 instance, allowing for quick and easy identification of any issues. Additionally, these tools can provide automated alerts when any issues are detected, allowing for quick and easy resolution of any issues.